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doi: 10.1172/JCI129484 66 MahajanATaliunDThurnerMRobertsonNRTorresJMRaynerNWet al

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The efficacy of evexomostat in inhibiting the angiogenic proteins FGF (Fibroblast growth factors) and VEGF (Vascular endothelial growth factor) was validated in a phase I clinical trial in advanced solid tumors (NCT02743637)

Furthermore, transgenic Drosophila models expressing human AD-associated genes, such as amyloid-beta (A) and tau, have enabled precise exploration of disease progression and therapeutic interventions (Table 13)