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The below chart outlines some of the key similarities and differences between once-weekly tirzepatide and injectable semaglutide

For a broader discussion of where different options sit in the treatment landscape, see this guide: Which weight loss drug is best

People with slower metabolism may have fatigue for longer than others

The NHS recommends regular washing with soap and water, particularly focusing on areas prone to sweating such as the underarms, groin, and feet, which can significantly reduce bacterial growth that contributes to odour

[11] [12] The primary mechanism of action involves binding to GLP-1 receptors located throughout the body, particularly in pancreatic beta cells, the gastrointestinal tract, and the central nervous system

Rybelsus is a daily oral medication approved to treat type 2 diabetes